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Three Decades of the Class A β-Lactamase Acyl-Enzyme

The discovery that the mechanism of β-lactam hydrolysis catalyzed by the class A (active site serine-dependent) β-lactamases proceeds via an acyl-enzyme intermediate was made thirty years ago. Since this discovery, the active site circumstance that enables acylation of the active site serine and fur...

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Detalhes bibliográficos
Publicado no:Curr Protein Pept Sci
Main Authors: Fisher, Jed F., Mobashery, Shahriar
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902449/
https://ncbi.nlm.nih.gov/pubmed/19538154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920309789351967
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