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Three Decades of the Class A β-Lactamase Acyl-Enzyme
The discovery that the mechanism of β-lactam hydrolysis catalyzed by the class A (active site serine-dependent) β-lactamases proceeds via an acyl-enzyme intermediate was made thirty years ago. Since this discovery, the active site circumstance that enables acylation of the active site serine and fur...
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| Published in: | Curr Protein Pept Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6902449/ https://ncbi.nlm.nih.gov/pubmed/19538154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920309789351967 |
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