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Purification, Reconstitution, and Inhibition of Cytochrome P-450 Sterol Δ(22)-Desaturase from the Pathogenic Fungus Candida glabrata
Sterol Δ(22)-desaturase has been purified from a strain of Candida glabrata with a disruption in the gene encoding sterol 14α-demethylase (cytochrome P-45051; CYP51). The purified cytochrome P-450 exhibited sterol Δ(22)-desaturase activity in a reconstituted system with NADPH–cytochrome P-450 reduct...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC89351/ https://ncbi.nlm.nih.gov/pubmed/10390230 |
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