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Dissection of NADPH-cytochrome P450 oxidoreductase into distinct functional domains.

NADPH-cytochrome P450 oxidoreductase transfers electrons from NADPH to cytochrome P450 and catalyzes the one-electron reduction of many drugs and foreign compounds. This enzyme is a flavoprotein containing the cofactors FMN and FAD, which are essential for its function. We have expressed the putativ...

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Detalhes bibliográficos
Main Authors: Smith, G C, Tew, D G, Wolf, C R
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC44676/
https://ncbi.nlm.nih.gov/pubmed/8078947
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