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Dissection of NADPH-cytochrome P450 oxidoreductase into distinct functional domains.

NADPH-cytochrome P450 oxidoreductase transfers electrons from NADPH to cytochrome P450 and catalyzes the one-electron reduction of many drugs and foreign compounds. This enzyme is a flavoprotein containing the cofactors FMN and FAD, which are essential for its function. We have expressed the putativ...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Smith, G C, Tew, D G, Wolf, C R
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44676/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8078947/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.18.8710
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