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Multiple Mechanisms of Action for Inhibitors of Histidine Protein Kinases from Bacterial Two-Component Systems

Many pathogenic bacteria utilize two-component systems consisting of a histidine protein kinase (HPK) and a response regulator (RR) for signal transduction. During the search for novel inhibitors, several chemical series, including benzoxazines, benzimidazoles, bis-phenols, cyclohexenes, trityls, an...

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Hlavní autoři: Hilliard, Jamese J., Goldschmidt, Raul M., Licata, Lisa, Baum, Ellen Z., Bush, Karen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89345/
https://ncbi.nlm.nih.gov/pubmed/10390224
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