Use of a Genetic Approach To Evaluate the Consequences of Inhibition of Efflux Pumps in Pseudomonas aeruginosa

Drug efflux pumps in Pseudomonas aeruginosa were evaluated as potential targets for antibacterial therapy. The potential effects of pump inhibition on susceptibility to fluoroquinolone antibiotics were studied with isogenic strains that overexpress or lack individual efflux pumps and that have vario...

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Detalhes bibliográficos
Main Authors: Lomovskaya, Olga, Lee, Angela, Hoshino, Kazuki, Ishida, Hiroko, Mistry, Anita, Warren, Mark S., Boyer, Eric, Chamberland, Suzanne, Lee, Ving J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89275/
https://ncbi.nlm.nih.gov/pubmed/10348749
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