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MexXY-OprM Efflux Pump Is Required for Antagonism of Aminoglycosides by Divalent Cations in Pseudomonas aeruginosa

Antagonism of aminoglycosides by divalent cations is well documented for Pseudomonas aeruginosa and is regarded as one of the problems in aminoglycoside therapy. It is generally considered that divalent cations interfere with uptake of aminoglycosides at both the outer and inner membranes. It has be...

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Detalhes bibliográficos
Main Authors: Mao, Weimin, Warren, Mark S., Lee, Angela, Mistry, Anita, Lomovskaya, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90592/
https://ncbi.nlm.nih.gov/pubmed/11408215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2001-2007.2001
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