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MexXY-OprM Efflux Pump Is Required for Antagonism of Aminoglycosides by Divalent Cations in Pseudomonas aeruginosa

Antagonism of aminoglycosides by divalent cations is well documented for Pseudomonas aeruginosa and is regarded as one of the problems in aminoglycoside therapy. It is generally considered that divalent cations interfere with uptake of aminoglycosides at both the outer and inner membranes. It has be...

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Main Authors: Mao, Weimin, Warren, Mark S., Lee, Angela, Mistry, Anita, Lomovskaya, Olga
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90592/
https://ncbi.nlm.nih.gov/pubmed/11408215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2001-2007.2001
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