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MexXY-OprM Efflux Pump Is Required for Antagonism of Aminoglycosides by Divalent Cations in Pseudomonas aeruginosa

Antagonism of aminoglycosides by divalent cations is well documented for Pseudomonas aeruginosa and is regarded as one of the problems in aminoglycoside therapy. It is generally considered that divalent cations interfere with uptake of aminoglycosides at both the outer and inner membranes. It has be...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Mao, Weimin, Warren, Mark S., Lee, Angela, Mistry, Anita, Lomovskaya, Olga
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90592/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11408215/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.7.2001-2007.2001
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