Inhibition of the Emergence of Ciprofloxacin Resistance in Streptococcus pneumoniae by the Multidrug Efflux Inhibitor Reserpine

Recent evidence supports the contribution of a multidrug efflux mechanism to fluoroquinolone resistance in Streptococcus pneumoniae. In this paper I show that reserpine, an inhibitor of multidrug transporters in gram-positive bacteria, dramatically suppresses the in vitro emergence of ciprofloxacin-...

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Veröffentlicht in:	Antimicrob Agents Chemother
1. Verfasser:	Markham, Penelope N.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Mechanisms of Resistance
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89246/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103220/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.988
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