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Inhibition of the Emergence of Ciprofloxacin Resistance in Streptococcus pneumoniae by the Multidrug Efflux Inhibitor Reserpine

Recent evidence supports the contribution of a multidrug efflux mechanism to fluoroquinolone resistance in Streptococcus pneumoniae. In this paper I show that reserpine, an inhibitor of multidrug transporters in gram-positive bacteria, dramatically suppresses the in vitro emergence of ciprofloxacin-...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Hovedforfatter: Markham, Penelope N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.988
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