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Potentiation of Isoniazid Activity against Mycobacterium tuberculosis by Melatonin

The limited number of effective antituberculosis drugs available necessitates optimizing current treatments. We show that melatonin, which is synthesized in the pineal gland, can cause at least a threefold increase in the efficacy of isoniazid. This suggests that tuberculosis chemotherapy can be imp...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Wiid, Ian, Hoal-van Helden, Eileen, Hon, Dinie, Lombard, Carl, van Helden, Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89241/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10103215/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.4.975
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