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Potentiation of Isoniazid Activity against Mycobacterium tuberculosis by Melatonin

The limited number of effective antituberculosis drugs available necessitates optimizing current treatments. We show that melatonin, which is synthesized in the pineal gland, can cause at least a threefold increase in the efficacy of isoniazid. This suggests that tuberculosis chemotherapy can be imp...

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Autors principals: Wiid, Ian, Hoal-van Helden, Eileen, Hon, Dinie, Lombard, Carl, van Helden, Paul
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89241/
https://ncbi.nlm.nih.gov/pubmed/10103215
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