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Potentiation of Isoniazid Activity against Mycobacterium tuberculosis by Melatonin

The limited number of effective antituberculosis drugs available necessitates optimizing current treatments. We show that melatonin, which is synthesized in the pineal gland, can cause at least a threefold increase in the efficacy of isoniazid. This suggests that tuberculosis chemotherapy can be imp...

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Detalhes bibliográficos
Main Authors: Wiid, Ian, Hoal-van Helden, Eileen, Hon, Dinie, Lombard, Carl, van Helden, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89241/
https://ncbi.nlm.nih.gov/pubmed/10103215
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