Characterization of ndh gene of isoniazid resistant and susceptible Mycobacterium tuberculosis isolates from Brazil

Resistance in Mycobacterium tuberculosis to isoniazid (INH) is caused by mutations in the catalase-peroxidase gene (katG) , and within the inhA promoter and/or in structural gene. A small percentage (~ 10%) of INH-resistant strains do not present mutations in both of these loci. Other genes have bee...

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Bibliografski detalji

Glavni autori:	Rosilene Fressatti Cardoso, Marco Antonio Cardoso, Clarice Queico Fujimura Leite, Daisy Nakamura Sato, Elsa Masae Mamizuka, Rosário Dominguez Crespo Hirata, Fernando Fiúza de Mello, Mario Hiroyuki Hirata
Format:	Artigo
Jezik:	Inglês
Izdano:	Fundação Oswaldo Cruz (FIOCRUZ) 2007-02-01
Serija:	Memorias do Instituto Oswaldo Cruz
Teme:	Mycobacterium tuberculosis NADH dehydrogenase gene isoniazid resistance
Online pristup:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762007000100009&lng=en&tlng=en
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