In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System

We investigated the correlation between an in vivo isobologram based on the concentrations of new quinolones (NQs) in brain tissue and the administration of nonsteroidal anti-inflammatory drugs (NSAIDs) for the occurrence of convulsions in mice and an in vitro isobologram based on the concentrations...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kita, Hideki, Matsuo, Hirotami, Takanaga, Hitomi, Kawakami, Junichi, Yamamoto, Koujirou, Iga, Tatsuji, Naito, Mikihiko, Tsuruo, Takashi, Asanuma, Atsushi, Yanagisawa, Keiji, Sawada, Yasufumi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89116/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10223919/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.5.1091
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