In Vivo and In Vitro Toxicodynamic Analyses of New Quinolone-and Nonsteroidal Anti-Inflammatory Drug-Induced Effects on the Central Nervous System

We investigated the correlation between an in vivo isobologram based on the concentrations of new quinolones (NQs) in brain tissue and the administration of nonsteroidal anti-inflammatory drugs (NSAIDs) for the occurrence of convulsions in mice and an in vitro isobologram based on the concentrations...

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Autores principales: Kita, Hideki, Matsuo, Hirotami, Takanaga, Hitomi, Kawakami, Junichi, Yamamoto, Koujirou, Iga, Tatsuji, Naito, Mikihiko, Tsuruo, Takashi, Asanuma, Atsushi, Yanagisawa, Keiji, Sawada, Yasufumi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC89116/
https://ncbi.nlm.nih.gov/pubmed/10223919
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