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An Alternative Animal Model for Comparison of Treatments for Cryptococcal Meningitis

Weanling outbred rats were infected with Cryptococcus neoformans by direct percranial puncture and inoculation into the cranium. A lethal infection ensued. Treatment with LY295337, a depsipeptide with antifungal activity, was effective in prolonging survival and reducing fungal counts in brain tissu...

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Bibliografiset tiedot
Päätekijät: Najvar, Laura K., Bocanegra, Rosie, Graybill, John R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 1999
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC89093/
https://ncbi.nlm.nih.gov/pubmed/9925548
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