Metabolic Studies on BMS-200475, a New Antiviral Compound Active against Hepatitis B Virus

BMS-200475 was recently shown to have potent antiviral activity against hepatitis B virus (50% effective concentration = 3.7 nM; 50% cytotoxic concentration = 30 μM). In metabolic studies in both HepG2 and hepatitis B virus-transfected 2.2.15 human hepatoma cell lines, the metabolism was similar, th...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yamanaka, Gregory, Wilson, Todd, Innaimo, Steven, Bisacchi, Gregory S., Egli, Peter, Rinehart, J. Kent, Zahler, Robert, Colonno, Richard J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1999
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC89048/
https://ncbi.nlm.nih.gov/pubmed/9869593
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares