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Loss of HuR Is Linked to Reduced Expression of Proliferative Genes during Replicative Senescence
Cellular aging is accompanied by alterations in gene expression patterns. Here, using two models of replicative senescence, we describe the influence of the RNA-binding protein HuR in regulating the expression of several genes whose expression decreases during senescence. We demonstrate that HuR lev...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87308/ https://ncbi.nlm.nih.gov/pubmed/11486028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5889-5898.2001 |
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