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Loss of CARM1 is linked to reduced HuR function in replicative senescence
BACKGROUND: The co-activator-associated arginine methyltransferase 1 (CARM1) catalyzes the methylation of HuR. However, the functional impact of this modification is not fully understood. Here, we investigated the influence of HuR methylation by CARM1 upon the turnover of HuR target mRNAs encoding s...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718661/ https://ncbi.nlm.nih.gov/pubmed/23837869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-14-15 |
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