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Phosphorylated HuR shuttles in cycles

HuR is a ubiquitous RNA-binding protein (RBP) that associates with many mRNAs encoding proliferative proteins. Although predominantly nuclear, HuR translocation to the cytoplasm is linked to its ability to stabilize target mRNAs and modulate their translation. We recently reported that HuR phosphory...

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Bibliographische Detailangaben
Hauptverfasser: Kim, Hyeon Ho, Gorospe, Myriam
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577782/
https://ncbi.nlm.nih.gov/pubmed/18927508
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