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Phosphorylated HuR shuttles in cycles

HuR is a ubiquitous RNA-binding protein (RBP) that associates with many mRNAs encoding proliferative proteins. Although predominantly nuclear, HuR translocation to the cytoplasm is linked to its ability to stabilize target mRNAs and modulate their translation. We recently reported that HuR phosphory...

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Detalles Bibliográficos
Main Authors: Kim, Hyeon Ho, Gorospe, Myriam
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577782/
https://ncbi.nlm.nih.gov/pubmed/18927508
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