Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase

AU-rich elements (ARE) present in the 3′ untranslated regions of many cytokines and immediate-early genes are responsible for targeting the transcripts for rapid decay. We present evidence from cotransfection experiments in NIH 3T3 cells that two signaling pathways, one involving phosphatidylinosito...

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Detalhes bibliográficos
Main Authors: Ming, Xiu-Fen, Stoecklin, Georg, Lu, Min, Looser, Renate, Moroni, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87297/
https://ncbi.nlm.nih.gov/pubmed/11486017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5778-5789.2001
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