Parallel and Independent Regulation of Interleukin-3 mRNA Turnover by Phosphatidylinositol 3-Kinase and p38 Mitogen-Activated Protein Kinase

AU-rich elements (ARE) present in the 3′ untranslated regions of many cytokines and immediate-early genes are responsible for targeting the transcripts for rapid decay. We present evidence from cotransfection experiments in NIH 3T3 cells that two signaling pathways, one involving phosphatidylinosito...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Ming, Xiu-Fen, Stoecklin, Georg, Lu, Min, Looser, Renate, Moroni, Christoph
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87297/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11486017/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.17.5778-5789.2001
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