Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover

To identify regulators of AU-rich element (ARE)-dependent mRNA turnover we have followed a genetic approach using a mutagenized cell line (slowC) that fails to degrade cytokine mRNA. Accordingly, a GFP reporter construct whose mRNA is under control of the ARE from interleukin-3 gives an increased fl...

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Main Authors: Stoecklin, Georg, Colombi, Marco, Raineri, Ines, Leuenberger, Sabrina, Mallaun, Michel, Schmidlin, Martin, Gross, Brigitte, Lu, Min, Kitamura, Toshio, Moroni, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126184/
https://ncbi.nlm.nih.gov/pubmed/12198173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf444
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