Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover
To identify regulators of AU-rich element (ARE)-dependent mRNA turnover we have followed a genetic approach using a mutagenized cell line (slowC) that fails to degrade cytokine mRNA. Accordingly, a GFP reporter construct whose mRNA is under control of the ARE from interleukin-3 gives an increased fl...
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| Veröffentlicht in: | EMBO J |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2002
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126184/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12198173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf444 |
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