Increased Susceptibility to Streptozotocin-Induced β-Cell Apoptosis and Delayed Autoimmune Diabetes in Alkylpurine- DNA-N-Glycosylase-Deficient Mice

Type 1 diabetes is thought to occur as a result of the loss of insulin-producing pancreatic β cells by an environmentally triggered autoimmune reaction. In rodent models of diabetes, streptozotocin (STZ), a genotoxic methylating agent that is targeted to the β cells, is used to trigger the initial c...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Cardinal, John W., Margison, Geoffrey P., Mynett, Kurt J., Yates, Allen P., Cameron, Donald P., Elder, Rhoderick H.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87281/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11463841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.16.5605-5613.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!