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Oncogenic Ras Blocks Anoikis by Activation of a Novel Effector Pathway Independent of Phosphatidylinositol 3-Kinase

Activated Ras, but not Raf, causes transformation of RIE-1 rat intestinal epithelial cells, demonstrating the importance of Raf-independent effector signaling in mediating Ras transformation. To further assess the contribution of Raf-dependent and Raf-independent function in oncogenic Ras transforma...

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Main Authors: McFall, Aidan, Ülkü, Aylin, Lambert, Que T., Kusa, Andrea, Rogers-Graham, Kelley, Der, Channing J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC87271/
https://ncbi.nlm.nih.gov/pubmed/11463831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5488-5499.2001
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