Oncogenic Ras differentially regulates metabolism and anoikis in extracellular matrix-detached cells

In order for cancer cells to survive during metastasis, they must overcome anoikis, a caspase-dependent cell death process triggered by extracellular matrix (ECM) detachment, and rectify detachment-induced metabolic defects that compromise cell survival. However, the precise signals used by cancer c...

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Bibliografske podrobnosti
izdano v:Cell Death Differ
Main Authors: Mason, J A, Davison-Versagli, C A, Leliaert, A K, Pape, D J, McCallister, C, Zuo, J, Durbin, S M, Buchheit, C L, Zhang, S, Schafer, Z T
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947665/
https://ncbi.nlm.nih.gov/pubmed/26915296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.15
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