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Activated ras Prevents Downregulation of Bcl-X(L) Triggered by Detachment from the Extracellular Matrix: A Mechanism of ras-Induced Resistance to Anoikis in Intestinal Epithelial Cells
Detachment of epithelial cells from the extracellular matrix (ECM) results in a form of apoptosis often referred to as anoikis. Transformation of intestinal epithelial cells by oncogenic ras leads to resistance to anoikis, and this resistance is required for the full manifestation of the malignant p...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
The Rockefeller University Press
2000
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175156/ https://ncbi.nlm.nih.gov/pubmed/10769035 |
| Etiketak: |
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