Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix

Detachment of non-malignant epithelial cells from the extracellullar matrix (ECM) triggers their growth arrest and apoptosis. Conversely, carcinoma cells can grow without adhesion to the ECM. This capacity for anchorage-independent growth is thought to be critical for tumor progression. ErbB2/Her2 o...

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Vydáno v:Oncotarget
Hlavní autoři: Khan, Iman A., Yoo, Byong H., Rak, Janusz, Rosen, Kirill V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739645/
https://ncbi.nlm.nih.gov/pubmed/29285258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22194
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