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Mek activity is required for ErbB2 expression in breast cancer cells detached from the extracellular matrix
Detachment of non-malignant epithelial cells from the extracellullar matrix (ECM) triggers their growth arrest and apoptosis. Conversely, carcinoma cells can grow without adhesion to the ECM. This capacity for anchorage-independent growth is thought to be critical for tumor progression. ErbB2/Her2 o...
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| Publicado en: | Oncotarget |
|---|---|
| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739645/ https://ncbi.nlm.nih.gov/pubmed/29285258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22194 |
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