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The Role of Multicellular Aggregation in the Survival of ErbB2-positive Breast Cancer Cells during Extracellular Matrix Detachment

The metastasis of cancer cells from the site of the primary tumor to distant sites in the body represents the most deadly manifestation of cancer. In order for metastasis to occur, cancer cells need to evade anoikis, which is defined as apoptosis caused by loss of attachment to extracellular matrix...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Rayavarapu, Raju R., Heiden, Brendan, Pagani, Nicholas, Shaw, Melissa M., Shuff, Sydney, Zhang, Siyuan, Schafer, Zachary T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4423663/
https://ncbi.nlm.nih.gov/pubmed/25681438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612754
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