Identification of an Overlapping Binding Domain on Cdc20 for Mad2 and Anaphase-Promoting Complex: Model for Spindle Checkpoint Regulation

Activation of the anaphase-promoting complex (APC) is required for anaphase initiation and for exit from mitosis in mammalian cells. Cdc20, which specifically recognizes APC substrates involved in the metaphase-to-anaphase transition, plays a pivotal role in APC activation through direct interaction...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Zhang, Yongke, Lees, Emma
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2001
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.15.5190-5199.2001
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