Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

The kinetochore checkpoint pathway, involving the Mad1, Mad2, Mad3, Bub1, Bub3 and Mps1 proteins, prevents anaphase entry and mitotic exit by inhibiting the anaphase promoting complex activator Cdc20 in response to monopolar attachment of sister kinetochores to spindle fibres. We show here that Cdc2...

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Hlavní autoři: Fraschini, Roberta, Beretta, Alessia, Sironi, Lucia, Musacchio, Andrea, Lucchini, Giovanna, Piatti, Simonetta
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125326/
https://ncbi.nlm.nih.gov/pubmed/11726501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6648
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