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Bub3 interaction with Mad2, Mad3 and Cdc20 is mediated by WD40 repeats and does not require intact kinetochores

The kinetochore checkpoint pathway, involving the Mad1, Mad2, Mad3, Bub1, Bub3 and Mps1 proteins, prevents anaphase entry and mitotic exit by inhibiting the anaphase promoting complex activator Cdc20 in response to monopolar attachment of sister kinetochores to spindle fibres. We show here that Cdc2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:EMBO J
Prif Awduron: Fraschini, Roberta, Beretta, Alessia, Sironi, Lucia, Musacchio, Andrea, Lucchini, Giovanna, Piatti, Simonetta
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2001
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125326/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11726501/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.23.6648
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