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Identification of an Overlapping Binding Domain on Cdc20 for Mad2 and Anaphase-Promoting Complex: Model for Spindle Checkpoint Regulation

Activation of the anaphase-promoting complex (APC) is required for anaphase initiation and for exit from mitosis in mammalian cells. Cdc20, which specifically recognizes APC substrates involved in the metaphase-to-anaphase transition, plays a pivotal role in APC activation through direct interaction...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Yongke, Lees, Emma
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC87243/
https://ncbi.nlm.nih.gov/pubmed/11438673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5190-5199.2001
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