Apoptosis Triggered by Myc-Induced Suppression of Bcl-X(L) or Bcl-2 Is Bypassed during Lymphomagenesis

Enforced Bcl-2 expression inhibits Myc-induced apoptosis and cooperates with Myc in transformation. Here we report that the synergy between Bcl-2 and Myc in transforming hematopoietic cells in fact reflects a Myc-induced pathway that selectively suppresses the expression of the Bcl-X(L) or Bcl-2 ant...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Eischen, Christine M., Woo, David, Roussel, Martine F., Cleveland, John L.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2001
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87232/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.15.5063-5070.2001
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