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Apoptosis Triggered by Myc-Induced Suppression of Bcl-X(L) or Bcl-2 Is Bypassed during Lymphomagenesis
Enforced Bcl-2 expression inhibits Myc-induced apoptosis and cooperates with Myc in transformation. Here we report that the synergy between Bcl-2 and Myc in transforming hematopoietic cells in fact reflects a Myc-induced pathway that selectively suppresses the expression of the Bcl-X(L) or Bcl-2 ant...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87232/ https://ncbi.nlm.nih.gov/pubmed/11438662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5063-5070.2001 |
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