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Phospholipase D Activity Is Required for Actin Stress Fiber Formation in Fibroblasts

Phospholipase D (PLD) is a ubiquitously expressed enzyme of ill-defined function. In order to explore its cellular actions, we inactivated the rat PLD1 (rPLD1) isozyme by tagging its C terminus with a V5 epitope (rPLD1-V5). This was stably expressed in Rat-2 fibroblasts to see if it acted as a domin...

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Detalles Bibliográficos
Main Authors: Kam, Yoonseok, Exton, John H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC87067/
https://ncbi.nlm.nih.gov/pubmed/11359912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.12.4055-4066.2001
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