B-Raf Acts via the ROCKII/LIMK/Cofilin Pathway To Maintain Actin Stress Fibers in Fibroblasts

Recent data have shown that the BRAF gene is mutated at a high frequency in human malignancies. We have analyzed the migratory characteristics of B-raf(−/−) mouse embryonic fibroblasts (MEFs) and compared these with the organization of the actin cytoskeleton and the activity of signaling pathways th...

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Bibliografiske detaljer
Main Authors: Pritchard, Catrin A., Hayes, Louise, Wojnowski, Leszek, Zimmer, Andreas, Marais, Richard M., Norman, Jim C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC480888/
https://ncbi.nlm.nih.gov/pubmed/15199148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.13.5937-5952.2004
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