B-Raf Acts via the ROCKII/LIMK/Cofilin Pathway To Maintain Actin Stress Fibers in Fibroblasts

Recent data have shown that the BRAF gene is mutated at a high frequency in human malignancies. We have analyzed the migratory characteristics of B-raf(−/−) mouse embryonic fibroblasts (MEFs) and compared these with the organization of the actin cytoskeleton and the activity of signaling pathways th...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Autores principales:	Pritchard, Catrin A., Hayes, Louise, Wojnowski, Leszek, Zimmer, Andreas, Marais, Richard M., Norman, Jim C.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Taylor & Francis 2004
Materias:	Cell Growth and Development
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC480888/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15199148/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.13.5937-5952.2004
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