Phospholipase D and RalA Cooperate with the Epidermal Growth Factor Receptor To Transform 3Y1 Rat Fibroblasts

3Y1 rat fibroblasts overexpressing the epidermal growth factor (EGF) receptor (EGFR cells) become transformed when treated with EGF. A common response to oncogenic and mitogenic stimuli is elevated phospholipase D (PLD) activity. RalA, a small GTPase that functions as a downstream effector molecule...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lu, Zhimin, Hornia, Armand, Joseph, Troy, Sukezane, Taiko, Frankel, Paul, Zhong, Minghao, Bychenok, Sergei, Xu, Lizhong, Feig, Larry A., Foster, David A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.462-467.2000
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