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Requirement of phospholipase D1 activity in H-Ras(V12)-induced transformation

The ability of the Ras oncogene to transform normal cells has been well established. One downstream effector of Ras is the lipid hydrolyzing enzyme phospholipase D. Recent evidence has emerged indicating a role for phospholipase D in cell proliferation, membrane trafficking, and migration. To study...

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Détails bibliographiques
Auteurs principaux: Buchanan, F. Gregory, McReynolds, Matt, Couvillon, Anthony, Kam, Yoonseok, Holla, Vijaykumar R., DuBois, Raymond N., Exton, John H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC547811/
https://ncbi.nlm.nih.gov/pubmed/15668389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406698102
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