Requirement of phospholipase D1 activity in H-Ras(V12)-induced transformation

The ability of the Ras oncogene to transform normal cells has been well established. One downstream effector of Ras is the lipid hydrolyzing enzyme phospholipase D. Recent evidence has emerged indicating a role for phospholipase D in cell proliferation, membrane trafficking, and migration. To study...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Buchanan, F. Gregory, McReynolds, Matt, Couvillon, Anthony, Kam, Yoonseok, Holla, Vijaykumar R., DuBois, Raymond N., Exton, John H.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 2005
Materias:	Biological Sciences
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC547811/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15668389/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0406698102
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