Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase

Emk is a serine/threonine protein kinase implicated in regulating polarity, cell cycle progression, and microtubule dynamics. To delineate the role of Emk in development and adult tissues, mice lacking Emk were generated by targeted gene disruption. Emk(−/−) mice displayed growth retardation and imm...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2001
Sujets:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.3206-3219.2001
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