Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase

Emk is a serine/threonine protein kinase implicated in regulating polarity, cell cycle progression, and microtubule dynamics. To delineate the role of Emk in development and adult tissues, mice lacking Emk were generated by targeted gene disruption. Emk(−/−) mice displayed growth retardation and imm...

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Bibliografski detalji
Glavni autori: Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC86958/
https://ncbi.nlm.nih.gov/pubmed/11287624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3206-3219.2001
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