Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase

Emk is a serine/threonine protein kinase implicated in regulating polarity, cell cycle progression, and microtubule dynamics. To delineate the role of Emk in development and adult tissues, mice lacking Emk were generated by targeted gene disruption. Emk(−/−) mice displayed growth retardation and imm...

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Bibliografiske detaljer
Main Authors: Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86958/
https://ncbi.nlm.nih.gov/pubmed/11287624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3206-3219.2001
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