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Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase

Emk is a serine/threonine protein kinase implicated in regulating polarity, cell cycle progression, and microtubule dynamics. To delineate the role of Emk in development and adult tissues, mice lacking Emk were generated by targeted gene disruption. Emk(−/−) mice displayed growth retardation and imm...

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Main Authors: Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC86958/
https://ncbi.nlm.nih.gov/pubmed/11287624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.3206-3219.2001
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