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Immune System Dysfunction and Autoimmune Disease in Mice Lacking Emk (Par-1) Protein Kinase

Emk is a serine/threonine protein kinase implicated in regulating polarity, cell cycle progression, and microtubule dynamics. To delineate the role of Emk in development and adult tissues, mice lacking Emk were generated by targeted gene disruption. Emk(−/−) mice displayed growth retardation and imm...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Hurov, Jonathan B., Stappenbeck, Thaddeus S., Zmasek, Christian M., White, Lynn S., Ranganath, Sheila H., Russell, John H., Chan, Andrew C., Murphy, Kenneth M., Piwnica-Worms, Helen
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86958/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.3206-3219.2001
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