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F-Box Protein Grr1 Interacts with Phosphorylated Targets via the Cationic Surface of Its Leucine-Rich Repeat

The flexibility and specificity of ubiquitin-dependent proteolysis are mediated, in part, by the E3 ubiquitin ligases. One class of E3 enzymes, SKp1/cullin/F-box protein (SCF), derives its specificity from F-box proteins, a heterogeneous family of adapters for target protein recognition. Grr1, the F...

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Autors principals: Hsiung, Yuchu G., Chang, Hui-Chu, Pellequer, Jean-Luc, La Valle, Roberto, Lanker, Stefan, Wittenberg, Curt
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86883/
https://ncbi.nlm.nih.gov/pubmed/11259599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.7.2506-2520.2001
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